COVID-19 Public Health North America January 8, 2021The US government has already spent considerable sums to fight the COVID-19 pandemic. Now, a modest new investment of around $12 billion to educate and encourage vaccine skeptics could hasten the pandemic’s end and add around $1 trillion to US GDP. Investing to support COVID-19-vaccine adoption could have outsize economic impact. Investment and potential return, $ billion Potential investment needed to support COVID-19 vaccine adoption at scale: $8–12 billion US Government spend on COVID-19-vaccine development, supply, and acquisition to date: 10$ billion US Government Public Health and Social Services Emergency Fund for COVID-19 response: 230$ billion Difference in US GDP between partially effective regional vaccine adoption versus widespread national vaccine adoption: $800–1,100 billion Source: Oxford University; US Department of Health and Human Services; US Government Accountability Office; McKinsey McKinsey & Company To read the article, see “COVID-19 vaccines meet 100 million uncertain Americans,” December 18, 2020.