The quarter’s top themes

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Top Ten Newsletter | Second Quarter 2025

In the second quarter of 2025, our top ten posts from McKinsey Themes highlight artificial intelligence, GLP-1s, geopolitical uncertainty, and more. At No. 1 is How AI is transforming 6 major industries, which features insights from McKinsey’s Alex Singla, Alexander Sukharevsky, Lareina Yee, and more. Read on for our full top 10.

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1. How AI is transforming 6 major industries

The latest McKinsey Global Survey on AI is out, and unsurprisingly, businesses are putting artificial intelligence to work across a wider range of functions than they did in 2024. Generate the most value

An image linking to the web page “The CEO’s guide: McKinsey’s latest insights on AI” on McKinsey.com.

2. The CEO’s guide: McKinsey’s latest insights on AI

As artificial intelligence is deployed across organizations, what steps can leaders take to drive bottom-line impact? Drive bottom-line impact

An image linking to the web page “How gen AI can take customer personalization to the next level” on McKinsey.com.

3. How gen AI can take customer personalization to the next level

The way customers interact with retailers and brands is evolving. To maintain an edge, companies should reevaluate their existing strategies and explore new avenues for growth. Reach the right consumers

4. GLP-1s are changing obesity care. What comes next?

Nearly 900 million adults globally live with obesity—a condition linked to at least 20 diseases and projected to cost the global economy $2.76 trillion in lost GDP by 2050. GLP-1 medications have emerged as a breakthrough treatment, with prescriptions growing 38 percent annually between 2022 and 2024 and sales expected to reach $100 billion by 2030. Learn more about the treatments

5. Gen AI in healthcare and life sciences: McKinsey’s latest insights

Gen AI is accelerating change in healthcare and life sciences. In healthcare, a recent McKinsey survey found that 85 percent of respondents—leaders from payers, health systems, and healthcare services and technology (HST) groups—are exploring or already using the technology. Stay up to date

6. The No. 1 best-selling guide to business valuation—updated for 2025

See what you’ll find in the recently published eighth edition of this seminal practitioner guide. Order the latest edition

7. How customer experience can help your business bloom

Positive brand experiences not only cultivate loyalty but also drive revenue growth, and today, any business can reap the benefits. The intersection of joy and surprise

8. Navigating geopolitical uncertainty: Perspectives from leading thinkers

Geopolitical conditions are no longer taking the back seat to macroeconomic, strategic, and operational concerns. Prepare, propel, and protect

9. A guide to navigating growing economic uncertainty

Tariffs and trade barriers are expanding rapidly, ushering in the first major global economic shock since the COVID-19 pandemic. Start building a nerve center

10. How women are reshaping the face of wealth

Female investors aren’t new—but their financial influence is growing faster than ever. 4 trends driving the shift

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