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Substance use disorders occur when the habitual use of alcohol, drugs, or both causes health problems and/or reduces a person’s ability to live their daily life as they otherwise would. Approximately 20 million adults have a substance use disorder. Substance use often co-occurs with mental illness—close to half of adults with a substance use disorder also experience a mental illness at the same time. Opioid addiction is rampant, and more than 130 people in the United States die every day after overdosing on opioids.

Opportunities for innovation we will pursue include novel strategies to help reduce the stigma around opioid addiction, models to reduce unjustified variation in prescribing patterns, and approaches to improve the efficacy of treatment for opioid-use disorder.

Featured insights


Why we need bolder action to combat the opioid epidemic

– Although the opioid crisis in the US is gaining increased attention, the steps taken to date to combat it are insufficient. Our... research suggests that much broader—and bolder—action is required.

Ten insights on the US opioid crisis from claims data analysis

– Careful analysis of health insurers’ claims data can provide important insights into the opioid crisis by identifying patterns... that could help shape strategies to combat opioid dependence and abuse.

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