Substance Use

Substance use disorders occur when the habitual use of alcohol, drugs, or both causes health problems and/or reduces a person’s ability to live their daily life as they otherwise would. Approximately 20 million adults have a substance use disorder. Substance use often co-occurs with mental illness—close to half of adults with a substance use disorder also experience a mental illness at the same time. Opioid addiction is rampant, and more than 130 people in the United States die every day after overdosing on opioids.

Opportunities for innovation we will pursue include novel strategies to help reduce the stigma around opioid addiction, models to reduce unjustified variation in prescribing patterns, and approaches to improve the efficacy of treatment for opioid-use disorder.